Diabetes mellitus
Description | Type 1: Fasting glucose in the mornings, the level should lie below 126 mg/dl (ADA 1997) (in venous plasma), oral glucose tolerance test (see function tests), if necessary with insulin- and peptide-evaluations, HbA1c, urine status, albumin in the urine (spontaneous or 24-hour urine), if necessary further proteinuria-diagnostics. Genetic markers: HLA-DR3 and -DR4 Autoantibodies (for risk estimation of post-partum type 1 diabetes):
Indication of antibody-evaluation:
Type 2: As per type 1 with additional: Cholestreol, LDL, HDL, triglycerides, if necessary lipid electrophoresis, Lp(a), homocysteine, CRP-ultrasensitive Checking of treatment: According to recent recommendations the HbA1c-value should be below 6,5 %. Etiological evaluation: Please see sections “Cushing, haemochromatosis, pancreatitis, hepatitis, acromegaly, hyperthyroidism and others” Exclusion of associated illnesses: Serological screening for gluten-sensitive enteropathy (sprue) in insulin-dependent diabetes patients. Molecular-genetic evaluation possible for: Maturity onset diabetes of the young (MODY)-type 1, 2 and 3 (type 2 diabetes at a young age) Please also refer to section: “gestational diabetes” Please also refer to the brochure “Current laboratory-medicinal aspects of type- and type 2-diabetes”. |
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