Colon and rectum carcinomas
| Description | Adeno-carcinoma: CEA, CA 19-9 or CA 72-4 Health screening: Sporadic colorectal carcinoma: In 1st degree relatives of patients with colorectal carcinoma or adenoma: Coloscopy from the age of 40 etc. (AWMF-guidelines) Hereditary colorectal carcinoma: Molecular-genetic evaluation (following human-genetic consultation): Mutations in the MLH1- and MSH2-genes in hereditary non-polypoid colorectal carcinoma (HNPCC) (10 % of all colorectal carcinoma) and in the APC-gene in familial adenomatous polyposis (FAP) (AWMF guidelines). |
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