Pancreolauryl test
| Indication | Suspicion of exocrine pancreatic insufficiency. Please note: According to newer studies, evaluation of pancreatic elastase in the stool is superior to the pancreolauryl test. |
| Material | 10 hour collection urine (minimum of 600 ml) each, on the test day and on the control day. |
| Procedure | The patient should drink 0,5 l non-sweetened tea at around 06:30 on the test morning. At 07 o’clock, the patients empties the bladder without collecting the urine. This is followed by breakfast, consisting of 1 roll with 20 g of butter, together with the two blue test capsules (these have to be swallowed without chewing) and one cup of tea. No further food intake until 10 o’clock. From 10 o’clock until 12 o’clock, a total of 1 l of tea needs to be drunk. From 1200 hours onwards, normal food intake, however vitamins and medication to support digestion should be avoided. The period for urine collection is from 07 o’clock to 1700 hours (10 hours in total) = sample A; the total urine quantity has to be a minimum of 600 ml! Repetition of the whole procedure (under equal conditions) after a minimum of 24 hours with swallowing the red tablet. Collected urine from 07 o’clock to 1700 hours (10 hours in total) = sample B. Take 20 ml of each sample and send in individually as “A” and “B”, stating the total volume of each sample (A and B). In the laboratory, the pigmentation of each urine sample is measured at wavelength 492 mm. |
| Evaluation | Normal exocrine pancreatic function: T/K quotient > 30
Pancreatic insufficiency: T/K quotient < 20, T/K quotient between 20 and 30: Repeat test. If T/K quotient is < 30 yet again, pancreatic insufficiency is likely. In case of slight exocrine pancreatic insufficiency, a false normal result can be seen. False negative test results will be received, if pancreatic enzyme substitution therapy is continued throughout the test.
Please note: False low pigmentation will be seen in case of incomplete urine collection and insufficient breakfast and capsule intake. |