Antibodies against LRP4
((low-density lipoprotein receptor-related protein 4))
| Material: | 1 ml serum |
| Methods: | Ligandenassays → Immunfluoreszenzassay (IFA) | Reference range | < 1:40 |
| Indication | Myasthenia gravis |
| Please note | Less commonly antibodies in ACh-R-antibody-negative myasthenia gravis (MG), prevalence in various studies differs considerably, the biggest series with 635 patients found LRP4-antibodies in 18,7 % of double-seronegative MG (Zisimopoulou P et al., J Autoimmun 2014; 52, 139–145); a smaller study with 100 patients found them in 2 % (Cordts I. et al., J Neurol 2017 Jun;264(6):1193-1203); LRP4-antibodies were also found, although rarely, together with ACh-R-antibodies or MuSK-antibodies. No association with thymomas. |
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