Methadon
| Material: | 10 ml urine, 2 ml serum (Stability in serum at 4°C – 8°C: 3 days), 100 g hair, saliva (Saliva collector available upon request), any other suspicious sample material, 10 ml gastric juice |
| Methods: |
Flüssigkeitschromatographie-Massenspektrometrie (LC-MS/MS) → LC-Tandem-Massenspektrometrie Ligandenassays → Enzyme Linked Immunosorbent Assay (ELISA) Ligandenassays → Enzym-Multiplied-Immunoassay (EMIT) | Reference range | Serum: < 50 µg/l |
| Indication | Substance abuse, substitution therapy, therapeutic drug monitoring |
| Therapeutic range | Serum: 50 – 500 µg/l |
| Please note | The determination of EDDP (Methadone metabolite) is by GC or LC-MS. There is no clear relationship between dose and serum concentration. Methadone is an opioid analgesic (analgesic potency is 2 – 4 times that of morphine). It is mainly used in the substitution therapy of opiate addicts. The side effect spectrum is typical of opiates/opioids. |
| Accredited | ja |
| Please also refer to: | Drug screening in urine |
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