Lead in the blood
(Pb)
Material: | 1 ml EDTA-blood |
Methods: | Spektrometrie → Atomabsorptionsspektroskopie (AAS) | Reference range | Men: < 90 µg/l Women: < 70 µg/l Children: < 35 µg/l |
Indication | Suspicion of acute or chronic poisoning (lead water pipes, workplace on busy roads, consumption of contaminated food). Acute poisoning: Colic, headaches, respiratory paralysis. Chronic poisoning: Paralysis of the radial nerve (wrist drop), discoloration of the gingiva (blue line, lead line), sub icteric discoloration of the conjunctivae, anemia. |
Please note | Tests in the past few years have shown, that blood lead levels of > 150 µg/l, which used to be classed as harmless in children, are now attributed to pose an increased risk for the cognitive development. Possible explanations are the low placental barrier for lead and the intestinal lead resorption rate of children, which is considerably higher in children than in adults. Accordingly, the limit value for children was lowered to 35 µg/l. On top of testing EDTA-blood, an additional measurement of porphyrines in 24-hour urine can be useful if chronic lead poisoning is suspected. Increased delta-aminolevulinic acid and coproporphyrin III levels are typical. |
Accredited | ja |
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