Felbamate
Material: | 1 ml serum |
Methods: | Flüssigkeitschromatographie-Massenspektrometrie (LC-MS/MS) → LC-Tandem-Massenspektrometrie |
Indication | Therapeutic drug monitoring |
Therapeutic range | 30 mg/l – 80 mg/l Alert level > 100 mg/l |
Please note | Felbamate works by blocking the NMDA-receptors and enhancing the effect of the inhibitory transmitter GABA. The effect mechanism has not yet been fully determined. Side effect spectrum covers nausea, vomiting, weight loss, sleepiness, vertigo, headaches and ataxia. |
Accredited | ja |
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