Ethosuximide
Material: | 1 ml serum (taken prior to next dose) |
Methods: | Hochleistungsflüssigkeitschromatographie (HPLC) → Hochleistungsflüssigkeitschromatographie (HPLC) |
Indication | Therapeutic drug monitoring |
Therapeutic range | 40 mg/l – 100 mg/l |
Please note | Ethosuximide is a succinimide derivate with antiepileptic effect. Effect mechanism is by blocking the calcium channels in the neurons of the thalamus. It only has a relatively minor toxicity. The most common problems in case of an overdose are nausea, anorexia, vomiting, restlessness, sleepiness, headaches, lethargy |
Accredited | ja |