Analysis index

1 ml serum

< 1,1 mg/l

Provisional assessment:

Low CHD risk: < 1,0 mg/l

Moderate CHD risk: 1,0 – 3,0 mg/l

High CHD risk: < 3,0 mg/l

Early recognition of atherosclerosis risk in healthy patients. Prognosis of cardiovascular morbidity and mortality in CHD patients. Prognosis of recurrence of myocardial infarction or stroke.           

In healthy as well as in patients with manifested atherosclerosis, CRP is a strong risk marker for cardiovascular events. In direct comparison with other inflammatory markers, lipoproteins and homocysteine, CRP had the highest forecast value for a future cardiovascular occurrence. Smoking, being overweight, suffering from type-2 diabetes or metabolic syndrome are associated with increased CRP-concentrations. The forecast value of US-CRP is especially high in combination with lipid values. It is assumed that slight systemic inflammation plays a central pathogenic role in the progression of atherosclerotic vascular changes. Please consider in the risk evaluation of coronary and peripheral vascular diseases, that CRP is a non-specific marker of inflammation. Accordingly, an increased value can only be evaluated by taking into account the complete clinical picture. Progress check are useful. Comparisons with previous values should always be done by critically assessing concurrent inflammatory processes. Therapeutic influence: Weight reduction, physical activity and statins may lower the CRP-concentration.