BRCA1 and BRCA2 mutation analysis
| Material: | 1 – 2 ml EDTA-blood and consent declaration, further material such as tumor biopsy material on request |
| Methods: | Amplifikationsverfahren → PCR und Sequenzierung |
| Indication | Diagnostic or predictive test in case of positive familial anamnesis for breast- and/or ovarial cancer. |
| Please note | Approximately 10 % of all breast cancers and 15 % of all ovarial cancers are by autosomal dominant inheritance and based on mutations in the BRCA1 and BRCA2 genes. Mutation carriers have an increased risk by up to 80 % of developing breast cancer and a 20 – 40 % risk for ovarial cancer. Caution: In case of predictive testing, human genetic counselling is required. |
| External services | ja MVZ Dr. Eberhard & Partner Dortmund |
More Results for the letter A
- Accompanying substances (BEGL)
- accompanying alcohols
- ACE (ACE)
- Angio-1 converting enzyme
- Acetone (ACET)
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- Acetylcholine receptor antibodies (AchR)
- AchR antibodies
- ACTH (ACTH)
- Adrenocorticotropic hormone
- Actinomycosis (KACTI)
- Actinomyces spp. I
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- Adrenal cortex autoantibodies (NNR)
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- Albumin in the serum (ALBUM)
- Albumin in urine (ALBUC)
- Alcohol in the blood (AETHS)
- Blood alcohol
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- Aldosterone/renin quotient (ARQ)
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- Regan isoenzyme
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- Type III allergy
- Allergy diagnostics (ALLERGIE)
- Alpha galactosidase in leucocytes (AGALA)
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