Anti-sickle cell desmosomes
| Material: | 1 ml serum |
| Methods: | Ligandenassays → Immunfluoreszenzassay (IFA) | Reference range | < 1:10 titer |
| Indication | Suspicion of pemphigus foliaceus, pemphigus vulgaris |
| Please note | Desmoglein 1 is the target antigen of pemphigus foliaceus and desmoglein 3 is that of pemphigus vulgaris. The titer correlates with disease activity. False-positive results: Burns, penicillin allergy, myasthenia gravis, lichen planus, SLE. Differential diagnosis pemphigoid: Autoantibodies against the epidermal basal membrane. |
| Accredited | ja |
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