Anti-SP100
(multiple nuclear dots)
Material: | 1 ml serum |
Methods: | Ligandenassays → Immunfluoreszenzassay (IFA) | Reference range | < 1:100 titer |
Indication | Suspicion of PBC in case of negative AMA, autoimmune hepatitis |
Please note | Antibodies against “nuclear dots” are directed against protein SP100 and mainly occur in patients with primary biliary cirrhosis (PBC) and autoimmune hepatitis. They are of differential diagnostic use especially in the 5 % of AMA-negative PBC patients. |
External services | ja Klinisch-immunologisches Labor Dr. Stöcker |
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