Anti-DNA antibodies
(ds-DNA antibodies (double-stranded))
| Material: | 1 ml serum |
| Methods: | Ligandenassays → Enzyme Linked Immunosorbent Assay (ELISA) | Reference range | < 100 IU/ml |
| Indication | Active stadium of SLE (sensitivity 70 %, specificity 98 %, for progress checks of SLE) |
| Please note | Constant low ds-DNA antibody titer point towards an inactive SLE with good prognosis. Sudden titer increase however suggests impending exacerbation. Evaluation of anti-ds-DNA is of utmost importance for the diagnosis of SLE, as it is very rarely found in medication-induced SLE, rheumatoid arthritis or Sjögren syndrome. In SLE patients with high antibody titers against ds-DNA, there is often kidney involvement. |
| External services | ja Labor Zentrum Weser Prof. Dr. med. Schmitz Minden |
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