LH
(Luteinizing hormone)
Material: | 1 ml serum (Stability in serum at 4 °C – 8 °C: 5 days) |
Methods: | Ligandenassays → Chemilumineszenz Mikropartikel Immunoassay (CMIA) | Reference range | Women: Men: Children: |
Indication | Women: Suspicion of primary and secondary ovarian insufficiency, suspicion of polycystic ovary syndrome, suspicion of menopause, suspicion of precocious menopause, suspicion of precocious puberty and delayed puberty Men: Suspicion of primary and secondary hypogonadism, delayed puberty and precocious puberty |
Please note | LH increase in the middle of the cycle triggers ovulation and initiates luteinization of the ruptured follicle by producing and secreting progesterone. After implantation of the fertilized egg, the luteotropic function of LH is replaced by that of beta-HCG, whose biological effect is virtually identical to the one of LH. A LH/FSH quotient of ≥ 2 indicates ovarian hyperandrogenism and may point to polycystic ovary syndrome. LH stimulates testosterone biosynthesis in the testicles by acting on the Leydig cells. An isolated Leydig cell damage in the testicles (primary hypogonadism) can therefore be identified by an increased LH value. |
Accredited | ja |
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