Ovarial insufficiency (OI)
Description | Hypergonadotropic OI LH, FSH increased, estradiol decreased, anti-mullarian-hormone Please refer to sections: “Menopause, precocious menopause, primary amenorrhea” Hypothalamic OI LH, FSH as well as estradiol and progesterone markedly decreased or normal. Exclusion diagnostics, as nearly all hormonal dysfunctions lead to changes of the GnRH-pulsatility and therefore LH- and FSH release. Please refer to sections “Anorexia nervosa, amenorrhea, oligomenorrhea” Hypophyseal OI LH, FSH decreased or within the lower reference range. Estradiol and progesterone decreased. Please refer to sections “Amenorrhea, oligomenorrhea, anterior pituitary insufficiency (Sheehan syndrome)” Hyperprolactinemic OI Prolactin, LH, FSH, TSH, testosterone, DHEAS, metoclopramide-test (function test) Please refer to sections “Hyperprolactinemia, galactorrhea, corpus luteum insufficiency, amenorrhea, oligomenorrhea, anovulation, fertility disorders” Hyperandrogenemic OI Stage 1: Testosterone, SHBG, free androgen index, DHEAS, if necessary androstendion, cortisol, LH, LH, FSH, estradiol Stage 2: Suspicion of adrenal hyperandrogenemia: DHEAS, 17-OH-progesterone, ACTH-test for exclusion of AGS (function test) Please refer to sections “Adrenogenital syndrome, hyperprolactinemia” Suspicion of Cushing syndrome: Cortisol day profile, dexamethasone test (see function tests) Suspicion of ovarial hyperandrogenemia: LH, FSH, estradiol, testosterone, SHBG Please refer to sections “Androgenisation, corpus luteum insufficiency, amenorrhea, oligomenorrhea, anovulation, fertility disorders, metabolic syndrome, hypothyroidism |
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