Osteoporosis
Description | Basic evaluations: Urine/EDTA-plasma: Pyridinolines in the 2nd morning urine, calcium and phosphate in the spontaneous urine or in the 24-hour urine, cross-laps (CTX) in the EDTA-plasma Clinical chemistry: Full blood count, ESR, CRP, alkaline phosphatase, AP-isoenzymes, calcium, phosphate, creatinine, GOT, GPT, gamma-GT Endocrinology: In women: Estradiol, FSH, LH In men: Testosterone, LH, FSH Molecular-genetic evaluations: COL1A1-gene mutation (collagen-type 1) VDR-gene mutation (Vitamin D-receptor-protein) ER-1-gene mutation (Estrogen-receptor-1-protein) Differential diagnosis of secondary osteoporosis:
Other causes: Acromegaly, vitamin D intoxication, immobilization, long-term heparin therapy, diabetes, liver diseases. In case of unclear osteoporosis, also consider non-classical type of Celiac disease/sprue (see there). Check on progress (every 3-6 months): Urine: Pyridinolines in the 2nd morning urine, calcium and phosphate in spontaneous urine or in 24-hour urine. Clinical chemistry: Alkaline phosphatase, AP-isoenzymes Endocrinology: Vitamin D; in women: Estradiol |
More Results for the letter O
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- Osteoporosis
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- Ovarial insufficiency (OI)
- Oxidative stress