Analysis index

1 ml serum
1 ml CSF
(Please note: Testing of a CSF-serum pair offer the highest diagnostic reliability and validity)  

Please refer to findings report

Autoimmune encephalitis, limbic encephalitis, autoimmune cerebellar syndrome, muscular hyperexcitability syndrome (Stiff person syndrome, Morvan syndrome, neuromyotonia), sleep and movement disorders in the context of autoimmune encephalitis – of both paraneoplastic genesis as well as without tumor association.

The standard program is a panel testing for neural antibodies. It covers all relevant neural antibodies for the above listed indications and is regularly updated to incorporate the latest findings and diagnostic possibilities.

It includes the following diagnostics:

Antibodies against surface antigens (IIF, cell based assay):
NMDAR, GAD 65, GABA-A-R, GABA-B-R, IgLON5, AMPAR1/2, DPPX, LGI1, CASPR2, mGluR5, Glycine-R, mGluR1

High-risk and related antibodies (previously known as well-defined onconeural antibodies) by Immunoblot containing these antigens:
Hu, Ma2/Ta, Ri, Yo, Sox1, CV2, DNER/Tr, Zic4, Amphiphysin, Recoverin, Titin (in case of positive findings, a confirmation by tissue based assay is sought = IIF on mouse brain)

Tissue based assay = IIF on mouse brain:
Confirmation test for onconeural antibodies, screening for neuropil antibodies, antibodies against adenylate kinase-5, ANNA3, Purkinje cells, GFAP, GAD 65, Neurexin 3-α, PCA-2, NIF