Estradiol
(Syn.: 17β-estradiol, E2)
Material: | 1 ml serum (Stability in serum at 4°C – 8°C: 3 days)
Estradiol values below 15 ng//l will be sent to you if requested. We would however like to point out that a sufficiently precise assessment of the measured value below 15 ng/l is no longer possible. |
Methods: | Ligandenassays → Chemilumineszenz Mikropartikel Immunoassay (CMIA) | Reference range | Women: Follicular stage: 15 ng/l – 250 ng/l Luteal phase: > 120 ng/l Post-menopausal: < 15 ng/l
Men: 15 ng/l – 45 ng/l |
Indication | Differential diagnosis of oligo menorrhea or amenorrhea, unfulfilled desire to have children, monitoring of hormone substitution with bioidentical estrogens |
Please note | Estradiol is produced nearly exclusively in the granulosa cells of the growing follicle with help of the aromatase from testosterone. During pregnancy, estradiol is synthetized in the placenta. After the menopause, estradiol concentration in the blood is very low. In case of follicular persistence, high estradiol levels (> 300 ng/l) are often measured. A so-called estrogen dominance with very high levels may also be present perimenopausal. When taking ovulation inhibitors with ethinyl estradiol or under postmenopausal hormone substitution with estrogen valerate, typically a suppressed estradiol level with low FSH and LH is measured. Bioidentical estrogens however are captured by the estradiol assay. A concomitant evaluation of progesterone, FSH and LH would be useful. |
Accredited | ja |
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- Syn.: 17β-estradiol, E2
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