Analysis index

1 ml serum, free of hemolysis

1 ml heparin plasma

(Stability in serum at 4°C – 8°C: 7 days)

Adults:

0,7 mmol/l – 1,1 mmol/l

(1,7 mg/dl – 2,67 mg/dl)

Children:

Please refer to findings report.

Suspicion of hypomagnesemia (normocalcemic tetany, tremor, cramps etc.), increased magnesium requirement (e.g. in pregnancy), arrhythmias

Magnesium, bar its structural function in the bones, is a co-factor of numerous enzymes, such as the sodium-potassium ATPase in the cell membrane. Intracellular accumulation of calcium is a consequence of magnesium deficiency and leads to muscular cramps, tetany, hypertension and cardiac arrhythmias, whilst hypermagnesemia leads to hypotension. Due to the intracellular sequestration of calcium, magnesium deficiency may also lead to concomitant hypocalcemia. Frequent causes of magnesium deficiency are malnutrition, intestinal malabsorption, treatment with diuretics (thiazides, loop diuretics), tubulopathies, osmotic diuresis and hyperparathyroidism. The most common cause of hypermagnesemia is acute or chronic kidney insufficiency.