Immunoglobulins, IgA in serum
| Material: | 1 ml serum (Stability in serum at 4°C – 8°C: 8 months) |
| Methods: | Spektrometrie → Nephelometrie | Reference range | Adults: 0,7 – 4,0 g/l Children: Please refer to findings report |
| Indication | Suspicion of immunoglobulin deficiency, monoclonal gammopathies |
| Please note | Frequency of a selective IgA-deficiency: 1:500 – 1:2000. In case of low IgA- levels, we recommend the evaluation of secretory IgA in saliva. An IgA-deficiency is often associated with other defects of the humoral and cellular immune system, allergies and autoimmune disorders (Celiac’s disease). Due to the frequent association with an IgG2 deficiency and IgG4 deficiency, an IgG-sub class evaluation is recommended. In patients with absolute IgA-deficiency and absent secretory IgA, the administration of blood products (plasma, immunoglobulins) may lead to the development of IgA-antibodies, which in turn may cause an anaphylactic reaction in case of repeat IgA application. Please also refer to section “Celiac’s disease” (Indications directory) |
| Accredited | ja |
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