Analysis index

2 ml sodium fluoride blood or sodium fluoride plasma (monovette tube with yellow top)

The immediate centrifugation of the sodium fluoride blood and the sending of sodium fluoride plasma is the best way. Storage at 4°C is recommended (Stability in sodium fluoride plasma at 4°C – 8°C: 7 days). Whole blood without supplement is not suitable. As per the current DDG guideline, a tube with sodium fluoride and citrate for immediate glycolysis inhibition must be used for the diagnostics of gestational diabetes mellitus. For this, the S-monovette GLUCOEXACT (grey top) is available. (Please ensure that the tube is filled correctly.)

Normal:

< 100 mg/dl (< 5,6 mmol/l)

Impaired fasting glucose:
100 mg/dl – 125 mg/dl (5,6 mmol/l – 6,9 mmol/l)

Manifest diabetes mellitus:
≥ 126 mg/dl (≥ 7,0 mmol/l):

Gestational diabetes:

Fasting glucose: < 92 mg/dl
50 g glucose load, independent of food intake but in non-fasting conditions (screening from 24+0 – 27+6 weeks of pregnancy):

After 60 min: < 135 mg/dl
75 g OGTT (following initial pathological screening or as initial diagnosis in 24+0 – 27+6 weeks of pregnancy screening), fasting:
basal: < 92 mg/dl (fasting)
after 60 minutes: < 180 mg/dl (60 minutes)
after 120 minutes: < 153 mg/dl (120 minutes)

Suspicion of gestational diabetes

If whole blood is taken (not recommended) instead of sodium fluoride blood or sodium fluoride plasma, there is a consumption of glucose due to the glycolysis in the erythrocytes. Storage at refrigerator temperature cannot prevent this sufficiently. An immediate centrifugation and division of the serum from the erythrocytes is required in any case.