Analysis index

Antibody demonstration: 1 ml serum, 2 ml CSF

Serum:

IgG: < 100 U/ml – 150 U/ml

IgM: < 10 U/ml – 15 U/ml

CSF: Please refer to findings report

Neurological symptoms after tick-bite, checking of immunity status (Booster vaccinations recommended every 4 – 5 years)

The laboratory has to report serological demonstration (IgM increase, fourfold IgG-antibody increase) to the health department, stating the patient’s name.

Vaccination recommendation for persons in endemic areas. After FSME- vaccination there is insufficient immunity in 10 % of the cases. Endemic regions: South Germany (Bavaria, Baden-Württemberg), Austria, Switzerland, Croatia, Albany, Russia, Latvia, Czech Republic, Slovenia. Ixodes ricinus is the carrier, please see RKI map “FSME: Risikogebiete in Deutschland”. Following a tick-bite initial onset of fever with flu-like symptoms. Then a fever-free interval for about a week. Following this, another bout of fever with neurological symptoms (meningitis, encephalitis). In approximately 10 % of cases, there is lasting neurological damage. In many cases however, the course of infection is subclinical. Differential diagnostically borreliosis, possibly Ehrlichiosis, rickettsiosis, ECHO-virus-infection has to be ruled out.