Analysis index

1 ml citrate plasma, frozen (unstable at 4°C – 8°C)

70% – 120%

Children: Please refer to findings report

• Evaluation of low Quick’s value without oral anticoagulation
• Suspicion of hereditary factor-VII-deficiency (prevalence 1:500.000)
• Suspicion of acquired factor-VII-deficiency (due to liver synthesis dysfunction)

Factor-VII is vitamin-K dependent. A decreased liver synthesis function is the most common cause of factor-VII-deficiency.

Guide to interpretation:

50 % – 70 %: sufficient hemostasis

25 % – 50 %: no increased tendency for bleeding, often also no decreased Quick’s value. Surgery with minor risk of bleeding can be carried out without substitution.

15 % – 25 %: increased risk of bleeding, in case of injuries and surgical procedures, a substitution should be given.

< 10 %: spontaneous and life-threatening bleeds (such as brain hemorrhages) are possible

When taking DOAKs (Dabigatran, Rivaroxaban, Apixaban or Edoxaban), an evaluation of the factor activity should be sought before the next dose.