Factor-II-mutation
(Prothrombin mutation G20210A)
| Material: | 1 ml EDTA-blood Swab from the mucosa of the inner side of the cheek (oral mucosal cells/dry swabs). A consent declaration in accordance with genetic diagnostics law is required! |
| Methods: | Amplifikationsverfahren → PCR und Sequenzierung |
| Indication | Suspicion of thrombophilia due to factor-II-mutation with increased incidence of venous thromboembolisms in the family. Stroke in patients below the age of 50. Patients after myocardial infarction. Relatives of patients with factor-II-mutation. |
| Comment | Please also refer to: Prothrombin-mutation |
| Please note | Prevalence of factor-II-mutation in the normal population is at approximately 1,7 % in Northern Europe and 3 – 5 % in Southern Europe. In patients with first time thromboembolism, prevalence is at 4 – 8 %. Thrombosis risk is increased by approximately x4,5 – 5 in factor-II-mutations of the heterozygous form. An unusual thrombosis localization associated with factor-II-mutation is the brain sinus, especially in young women who are on oral contraceptives. |
| Accredited | ja |
| Please also refer to: | Prothrombin-Mutation |
More Results for the letter F
- Factor II activity (FACT01)
- Prothrombin
- Factor II mutation (FACT02)
- Prothrombin mutation G20210A
- Factor IX activity (FACT11)
- Factor V activity (FACT03)
- Factor V mutation Leiden (FACT04)
- Mutation: G1691A
- Factor VII activity (FACT05)
- Factor VIII activity (FACT06)
- Factor VIII inhibitor (FACT10)
- Factor VIII ristocetin cofactor (von Willebrand factor activity) (FACT08)
- vWF:activity
- Factor VIII von Willebrand factor antigen (FACT07)
- vWF:Ag
- Factor VIII von Willebrand multimers (FACT09)
- Factor X activity (FACT12)
- Factor XI activity (FACT13)
- Factor XII activity (FACT14)
- Hageman-Factor
- Factor XIII activity (FACT15)
- Syn.: fibrin stabilising factor
- Factor–II–activity (FAK2)
- Prothrombin
- Factor-II-mutation (FAK2GM)
- Prothrombin mutation G20210A
- Factor-IX-activity (FAK9)
- Factor-V-activity (FAK5)
- Factor-V-mutation Leiden (FAK5GM)
- Mutation: G1691A
- Factor-VII-activity (FAK7)
- Factor-VIII-activity (FAK8)
- Factor-VIII-inhibitor (FAK8IN)
- Bethesda assay
- Factor-X-activity (FAK10)
- Factor-XI-activity (FAK11)
- Factor-XII-activity (FAK12)
- Hageman factor
- Factor-XIII-activity (FAK13)
- Fibrin-stabilizing factor
- Fasciola hepatica (FASCI, FASCG)
- Common liver fluke
- Fat, total in stool (FETT1)
- Fatty acids, long-chained (LAFS)
- LCFA