D-dimers
(Fibrin split products)
Material: | 1 ml citrate plasma (Stability in citrate plasma at 20°C – 25°C: 12 – 24 hours) |
Methods: | Spektrometrie → Nephelometrie | Reference range | < 340 ng/ml FEU (Fibrinogen equivalent units) |
Indication | - Exclusion of acute primary deep leg vein thrombosis, pulmonary embolism - Progress checks in case of disseminated intravascular coagulation - Progress checks in risk pregnancies (HELLP-syndrome) - Risk analysis of recurrent vein thrombosis
In the treatment of deep vein thrombosis and pulmonary embolism, often there is a 6-months anticoagulation period with low molecular heparin or marcumar (i.e. initial manifestation, temporary reason). It is then tested whether therapy may be discontinued. Of help in this decision making process is the d-dimer concentration, which should be within normal values. Around 15 % of patients show increased d-dimer-levels at the end of secondary prophylaxis treatment or after its discontinuation. Those patients have a higher recurrence risk than patients with normal d-dimers. |
Please note | The immunoassay used by us (TriniLIA D-Dimer-Test) with a limiting value of 340 ng/ml FEU in patients below the age of 60, has a negative predictive forecast value (probability of not having a disorder in case of a negative test result) of 96 %. Therefore, a normal d-dimer concentration (< 340 ng/ml FEU) rules out deep leg vein thrombosis or pulmonary embolism with high probability. On the other hand, due to the low specificity (< 50 %), an increased d-dimer concentration is not indicative of thrombosis, as many other causes (inflammations, infections etc.) can be the reason for high concentrations in the blood. No definite statement is possible when treatment with heparin or anticoagulants has already commenced. |
Accredited | ja |
More Results for the letter D
- D-dimers (FSP)
- Fibrin split products
- DDE/DDT (DDT)
- Dengue-virus infection (DENGUE)
- Arboviruses
- Dermatophyte infection (DERM)
- skin mycosis: superficial and deep Trichophyton infections; Microsporon - superficial infections; Epidermophyton infections
- Dermatophytes infection (MDERM)
- Skin fungus, onychomycosis, tinea
- Desipramine (DES)
- Desoxycortisol (11-) (11D)
- DHEAS (DHEA)
- Dehydroepiandrosterone-sulfate
- Diamine oxidase (DAO)
- Diazepam (DIAZ)
- Dibucaine number (DIBUC)
- Cholinesterase variants
- Digitoxin (DIGI)
- Digoxin (DIGO)
- Dihydrocodeine (DIHYD)
- Diphenhydramine (HPLC) (DIPHHY)
- Diphtheria (DIPH)
- Corynebacterium diphtheriae
- Diphyllobothrium latum (APARA)
- Fish tapeworm
- DNA antibodies (DNAA)
- Donath-Landsteiner antibodies (KAEA37)
- Paroxysmal cold hemoglobinuria
- Doxepin (DOX)
- DPD gene analysis (DPDG)
- Dihydropyrimidine dehydrogenase
- DPD-gene analysis (DPD)
- Dihydropyrimidine dehydrogenase
- Drinking water, analysis (DRIN)
- Drug screening in hair (HAARM)
- Drug screening in saliva (SPEIL)
- Drug screening in urine (DRU1-3)
- Duloxetine (DULO)
- Dysbacteria (DYSB)